Fig. 1 · Structure

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Biotin-PEG5-NH-Boc

PROTAC Linkers

Biotin-PEG5-NH-Boc is a PEG-based linker designed for use in Protein Degradation Targeting Chimera (PROTAC) synthesis. This compound facilitates the conjugation of biotinylated moieties to target proteins, enhancing the efficacy of PROTACs in promoting targeted protein degradation. It serves as a crucial component in research applications focused on protein modulation and therapeutic development strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 189209-28-7
Applications PROTAC Linkers
Formula C27H50N4O9S
Molecular Weight 606.77
SMILES
O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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