Fig. 1 · Structure

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Biotin-PEG6-NH-Boc

PROTAC Linker

Biotin-PEG6-NH-Boc is a PEG-based linker designed for use in the synthesis of PROTACs. This compound facilitates the creation of PROTAC molecules by providing a biotinylated moiety, which allows for the targeted degradation of proteins through the ubiquitin-proteasome system. It is particularly valuable in research focusing on targeted protein degradation and the development of innovative therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1292268-20-2
Applications PROTAC Linker
Formula C29H54N4O10S
Molecular Weight 650.82
SMILES
CC(C)(C)OC(NCCOCCOCCOCCOCCOCCOCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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