Fig. 1 · Structure
Documents & Downloads
Biotin-PEG7-amine
PROTAC Linker
Biotin-PEG7-amine is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its primary mechanism involves facilitating the recruitment of E3 ligases to target proteins for ubiquitination and subsequent degradation. This compound plays a crucial role in the development of targeted protein degradation strategies, enabling researchers to manipulate protein levels in various biological contexts. Biotin-PEG7-amine is essential for advancing research in the field of targeted therapies and cellular protein regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1334172-76-7 |
| Applications | PROTAC Linker |
| Formula | C26H50N4O9S |
| Molecular Weight | 594.76 |
| SMILES | O=C(NCCOCCOCCOCCOCCOCCOCCOCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.