Fig. 1 · Structure
Documents & Downloads
Biotin-PEG8-amine
PROTAC Linkers
Biotin-PEG8-amine is a biotinylated linker with a polyethylene glycol (PEG) moiety designed for use in PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound enhances the solubility and stability of PROTAC molecules, facilitating targeted protein degradation in cellular studies. Its biotin functionality also allows for efficient capture and purification of PROTACs via streptavidin-based methods, enabling exploration of protein interactions and functional assays in chemical biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2183447-27-8 |
| Applications | PROTAC Linkers |
| Formula | C28H54N4O10S |
| Molecular Weight | 638.81 |
| SMILES | O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCN)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.