Fig. 1 · Structure
Documents & Downloads
Biotin-PFP ester
PROTAC Linker
Biotin-PFP ester is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This alkyl/ether-based compound enhances molecular recognition through biotinylation, enabling selective degradation of target proteins via the ubiquitin-proteasome pathway. Its utility in the development of targeted protein degradation strategies makes it valuable for research applications in cancer biology and therapeutic discovery.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 120550-35-8 |
| Applications | PROTAC Linker |
| Formula | C16H15F5N2O3S |
| Molecular Weight | 410.36 |
| SMILES | O=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(OC3=C(C(F)=C(C(F)=C3F)F)F)=O)[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.