Biotin-PFP ester

Catalog No.: A81959
PROTAC Linker
Biotin-PFP ester is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This alkyl/ether-based compound enhances molecular recognition through biotinylation, enabling selective degradation of target proteins via the ubiquitin-proteasome pathway. Its utility in the development of targeted protein degradation strategies makes it valuable for research applications in cancer biology and therapeutic discovery.
Grouped product items
Size Price Stock Qty
100mg
$40.00
In stock
250mg
$50.00
In stock
1g
$135.00
In stock
5g
$485.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBiotin-PFP ester is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This alkyl/ether-based compound enhances molecular recognition through biotinylation, enabling selective degradation of target proteins via the ubiquitin-proteasome pathway. Its utility in the development of targeted protein degradation strategies makes it valuable for research applications in cancer biology and therapeutic discovery.
Product Information
Catalog NumA81959
FormulaC16H15F5N2O3S
Molecular Weight410.36
CAS Number120550-35-8
SMILESO=C1N[C@]2(CS[C@H]([C@]2(N1)[H])CCCCC(OC3=C(C(F)=C(C(F)=C3F)F)F)=O)[H]
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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