Fig. 1 · Structure

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Bis-(m-PEG4)-amidohexanoic acid

PROTAC Linkers

Bis-(m-PEG4)-amidohexanoic acid is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound enables the formation of stable and efficient PROTACs, facilitating the selective degradation of target proteins. It serves as a crucial tool in drug development and molecular biology research, particularly for studying protein interactions and the modulation of cellular pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2353409-74-0
Applications PROTAC Linkers
Formula C26H50N2O12
Molecular Weight 582.68
SMILES
OC([C@@H](CCCCNC(CCOCCOCCOCCOC)=O)NC(CCOCCOCCOCCOC)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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