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Bis-Mal-PEG6

PROTAC Linkers

Bis-Mal-PEG6 is a polyethylene glycol (PEG)-based linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This bifunctional molecule facilitates the conjugation of ligands to E3 ligases, enabling targeted degradation of proteins within cells. Its application in PROTAC development supports research in areas such as targeted protein degradation and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2458811-07-7
Applications	PROTAC Linkers
Formula	C₂₈H₄₂N₄O₁₂
Molecular Weight	626.65
SMILES	O=C(NCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)CCN2C(C=CC2=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.