Fig. 1 · Structure

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Bis(maltolato)oxovanadium(IV)

PTP Inhibitor

Bis(maltolato)oxovanadium(IV) is a reversible, competitive inhibitor targeting protein tyrosine phosphatases (PTPs). It demonstrates significant inhibitory activity against HCPTPA, PTP1B, HPTPβ, and SHP2, with IC50 values of 126 nM, 109 nM, 26 nM, and 201 nM, respectively. This compound serves as a powerful insulin sensitizer, making it a valuable tool for research in metabolic disorders and diabetes-related studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 38213-69-3
Applications PTP Inhibitor
Formula C12H10O7V
Molecular Weight 317.15
Synonyms BMOV
SMILES
O=[V+2]([O-]C1=C2C)([O]=C1C=CO2)([O]=C3C=CO4)[O-]C3=C4C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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