Fig. 1 · Structure

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Bis-methacrylate-PEG5

PROTAC Linker

Bis-methacrylate-PEG5 is a polyethylene glycol (PEG)-based linker designed for PROTAC (PROteolysis TArgeting Chimeras) synthesis. This flexible linker facilitates the effective conjugation of target proteins to E3 ligases, enhancing the targeted degradation of specific proteins within cells. Its unique properties make it suitable for research applications focused on protein degradation and cellular pathways modulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 13497-24-0
Applications PROTAC Linker
Formula C18H30O8
Molecular Weight 374.43
SMILES
CC(C(OCCOCCOCCOCCOCCOC(C(C)=C)=O)=O)=C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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