Bis-PEG1-PFP ester

Catalog No.: A43174
ADC Linker
Bis-PEG1-PFP ester is a non-cleavable linker designed for antibody-drug conjugate (ADC) synthesis, featuring a single unit of polyethylene glycol (PEG). This reagent facilitates the conjugation of antibodies with cytotoxic agents, maintaining stability during circulation. Its unique properties make it suitable for enhancing the therapeutic efficacy of ADCs while minimizing off-target effects, making it invaluable for cancer research and drug development.
Grouped product items
Size Price Stock Qty
25mg
$80.00
In stock
50mg
$120.00
In stock
100mg
$180.00
In stock
250mg
$315.00
In stock
1g
$875.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBis-PEG1-PFP ester is a non-cleavable linker designed for antibody-drug conjugate (ADC) synthesis, featuring a single unit of polyethylene glycol (PEG). This reagent facilitates the conjugation of antibodies with cytotoxic agents, maintaining stability during circulation. Its unique properties make it suitable for enhancing the therapeutic efficacy of ADCs while minimizing off-target effects, making it invaluable for cancer research and drug development.
Product Information
Catalog NumA43174
FormulaC18H8F10O5
Molecular Weight494.24
CAS Number1807539-02-1
SMILESO=C(OC1=C(F)C(F)=C(F)C(F)=C1F)CCOCCC(OC2=C(F)C(F)=C(F)C(F)=C2F)=O
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