Bis-Tos-(2-hydroxyethyl disulfide)

Catalog No.: A43017
ADC Linker
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the selective release of therapeutic agents upon cellular uptake, enhancing the efficacy of targeted cancer therapies. Its bioactive properties make it suitable for various research applications in the development of ADCs, allowing for precise drug delivery and improved patient outcomes in oncology studies.
Grouped product items
Size Price Stock Qty
2mg
$30.00
In stock
5mg
$45.00
In stock
10mg
$65.00
In stock
100mg
$160.00
In stock
500mg
$505.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBis-Tos-(2-hydroxyethyl disulfide) is a cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the selective release of therapeutic agents upon cellular uptake, enhancing the efficacy of targeted cancer therapies. Its bioactive properties make it suitable for various research applications in the development of ADCs, allowing for precise drug delivery and improved patient outcomes in oncology studies.
Product Information
Catalog NumA43017
FormulaC18H22O6S4
Molecular Weight462.62
CAS Number69981-39-1
SMILESO=S(C1=CC=C(C)C=C1)(OCCSSCCOS(C2=CC=C(C)C=C2)(=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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