Fig. 1 · Structure
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Bisaramil
Antiarrhythmic Agent
Bisaramil is an orally active antiarrhythmic agent that targets cardiac ion channels to modulate electrical activity in the heart. This compound exhibits a concentration-dependent inhibitory effect on phorbol 12-myristate 13-acetate (PMA)-stimulated free radical generation, thereby prolonging the time lag in cardiac responses. Bisaramil serves as a valuable tool for research focused on cardiac arrhythmias and oxidative stress-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 89194-77-4 |
| Applications | Antiarrhythmic Agent |
| Formula | C17H23ClN2O2 |
| Molecular Weight | 322.83 |
| SMILES | O=C(C1=CC=C(Cl)C=C1)O[C@]2([C@H]3CN(CC)C[C@@H]2CN(C)C3)[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.