Fig. 1 · Structure
Documents & Downloads
Bisnorcymserine
BChE Inhibitor
Bisnorcymserine is a potent inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 0.228 nM. This compound effectively reduces levels of amyloid-β peptide (Aβ) and has demonstrated therapeutic potential in ameliorating symptoms of Alzheimer's Disease in aged rat models. Bisnorcymserine's ability to penetrate the blood-brain barrier makes it a valuable tool for research in neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 219920-81-7 |
| Applications | BChE Inhibitor |
| Formula | C21H25N3O2 |
| Molecular Weight | 351.44 |
| Synonyms | N1,N8-Bisnorcymserine; (-)-Bisnorcymserine |
| SMILES | O=C(NC1=CC=C(C=C1)C(C)C)OC2=CC3=C(C=C2)N[C@@]4([C@]3(CCN4)C)[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.