Fig. 1 · Structure
Documents & Downloads
BJJF078
TG2/TG1 Inhibitor
BJJF078 is a potent inhibitor of transglutaminase 2 (TG2) and transglutaminase 1 (TG1), with IC50 values of 41 nM and 0.16 μM, respectively. This aminopiperidine derivative demonstrates significant inhibition of TG2 activity in both human and mouse recombinant forms. BJJF078 is primarily utilized in research focused on multiple sclerosis (MS), facilitating investigations into the role of transglutaminases in disease pathology and potential therapeutic interventions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2531244-56-9 |
| Applications | TG2/TG1 Inhibitor |
| Formula | C27H29N3O6S |
| Molecular Weight | 523.60 |
| SMILES | O=C(NC1CCN(S(=O)(C2=C3C=CC=C(NC(C4=CC=C(C(OC)=C4)OC)=O)C3=CC=C2)=O)CC1)C=C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.