Fig. 1 · Structure
Documents & Downloads
BKM-570
Bradykinin Antagonist
BKM-570 is a nonpeptide bradykinin antagonist that exhibits significant anticancer properties. This compound is valuable for research applications focusing on lung, prostate, and ovarian cancers, providing insights into the role of bradykinin signaling in tumor biology and potential therapeutic approaches. Its antagonistic action contributes to the understanding of bradykinin's involvement in cancer progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 259885-54-6 |
| Applications | Bradykinin Antagonist |
| Formula | C34H34Cl2F5N3O3 |
| Molecular Weight | 698.55 |
| SMILES | O=C([C@@H](NC(/C=C/C1=C(C(F)=C(C(F)=C1F)F)F)=O)CC2=CC=C(C=C2)OCC3=C(C=CC=C3Cl)Cl)NC4CC(C)(C)NC(C)(C)C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.