Fig. 1 · Structure

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BL20-MMAE

Cat. No. A41753 CAS 2765612-38-0

ROR1 ADC Intermediate

BL20-MMAE is an antibody-drug conjugate designed to target the receptor tyrosine kinase ROR1. This compound is synthesized by linking an anti-ROR1 antibody with the cytotoxic agent MMAE through a BL20 linker, facilitating targeted delivery of the drug. BL20-MMAE is primarily utilized in research applications focused on cancer therapeutics, particularly in studies involving ROR1-positive malignancies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2765612-38-0
Applications ROR1 ADC Intermediate
Formula C98H133F2N13O23S2
Molecular Weight 1963.30
SMILES
O=C(N1CCOCC1)C(C=C2)=CC=C2SC(C(N(C3=CC(F)=C(C(F)=C3)OCCOCCOCCOCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC4=CC=C(C=C4)COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N5[C@](CCC5)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C6=CC=CC=C6)O)=O)=O)=O)=O)=O)=O)=O)=O)C7=O)=O)=C7SC8=CC=C(C=C8)C(N9CCOCC9)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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