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BLX-2477

Name: BLX-2477
Brand: Adooq Bioscience
SKU: A76491
Availability: OutOfStock

Cat. No. A76491 CAS 1080008-87-2

15-Lipoxygenase-1 Inhibitor

BLX-2477 is a potent and selective inhibitor of 15-lipoxygenase-1 (15-LOX-1), demonstrating an IC50 value of 99 nM. This compound effectively inhibits the production of inflammatory lipid mediators, including 15-hydroxy-eicosatetraenoic acid (15-HETE). BLX-2477 is suitable for research applications in the fields of inflammation and immunology, facilitating the study of related biological processes and potential therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1080008-87-2
Applications	15-Lipoxygenase-1 Inhibitor
Formula	C₉H₆Cl₂N₄O
Molecular Weight	257.08
SMILES	O=C(C1=NNN=C1)NC2=CC=C(Cl)C=C2Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.