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Biological Activity
BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor, with IC50s of 9 nM and 72 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.36 mL | 131.78 mL | 263.56 mL |
| 0.5 mM | 5.27 mL | 26.36 mL | 52.71 mL |
| 1 mM | 2.64 mL | 13.18 mL | 26.36 mL |
| 5 mM | 0.53 mL | 2.64 mL | 5.27 mL |
*The above data is based on the productmolecular weight 379.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21972 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 914946-88-6 |
| Formula | C19H21N7O2 |
| M. Wt | 379.42 |
| Purity | >98% |
| Synonyms | BMS066, BMS 066 |
| SMILES | CN1C=NC2=C1C(C=C(C3=CC=CC(CNC(COC)=O)=N3)N4)=C4N=C2NC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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