Total item
Cart Subtotal
$0.00 Biological Activity
BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
| In vitro | DMSO | 91 mg/mL (141.93 mM) | |
| Water | Insoluble | ||
| Ethanol | 12 mg/mL (18.71 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.6 mL | 77.99 mL | 155.98 mL |
| 0.5 mM | 3.12 mL | 15.6 mL | 31.2 mL |
| 1 mM | 1.56 mL | 7.8 mL | 15.6 mL |
| 5 mM | 0.31 mL | 1.56 mL | 3.12 mL |
*The above data is based on the productmolecular weight 641.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13129 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1818314-88-3 |
| Formula | C36H33ClN2O7 |
| M. Wt | 641.11 |
| Purity | >98% |
| Synonyms | BMS 1166, BMS1166 |
| SMILES | O=C(O)[[email protected]@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[[email protected]](O)C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy BMS-1166 | BMS-1166 Supplier | purchase | cost | manufacturer | order | distributor | buy 1818314-88-3| 1818314-88-3 Supplier | purchase 1818314-88-3 | 1818314-88-3 cost | 1818314-88-3 manufacturer | order 1818314-88-3 | 1818314-88-3 distributor
Adooq Quality Guarantee
We promise all products perform as described.