BMS-1166

Catalog No.: A13129

PD-1/PD-L1 interaction inhibitor

BMS-1166

BMS-1166 Chemical Structure

CAS NO. 1818314-88-3

BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

Availability: In stock

Package Price Qty
5 mg
$450.00
10 mg
$775.00
50 mg
$2,300.00
100 mg
$4,600.00
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Biological Activity

BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.6 mL 77.99 mL 155.98 mL
0.5 mM 3.12 mL 15.6 mL 31.2 mL
1 mM 1.56 mL 7.8 mL 15.6 mL
5 mM 0.31 mL 1.56 mL 3.12 mL

*The above data is based on the productmolecular weight 641.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13129
Actions Inhibitor
M. Wt 641.11
Formula C36H33ClN2O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1818314-88-3
Synonyms BMS 1166, BMS1166
SMILES O=C(O)[[email protected]@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[[email protected]](O)C1

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