Fig. 1 · Structure
Documents & Downloads
BMS-186511
Farnesyltransferase Inhibitor
BMS-186511 is a selective farnesyltransferase inhibitor that disrupts the post-translational modification of proteins critical for cancer cell growth and survival. This compound exhibits notable anticancer activity and is utilized in research to explore mechanisms of tumorigenesis and potential therapeutic strategies in oncology. Its application in cancer research makes it a valuable tool for studying the role of farnesylation in various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 167467-53-0 |
| Applications | Farnesyltransferase Inhibitor |
| Formula | C34H60N3O7PS |
| Molecular Weight | 685.89 |
| SMILES | CSCC[C@@H](C(OC)=O)NC([C@H](C(C)C)NC([C@H](C(C)C)NC(CCP(C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)(O)=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.