Fig. 1 · Structure

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BMS-214662 mesylate

Farnesyl Transferase Inhibitor

BMS-214662 mesylate is a highly selective inhibitor of farnesyl transferase, demonstrating an IC50 of 1.35 nM. This compound exhibits significant antitumor activity, making it a valuable tool in cancer research. Its ability to impede farnesylation provides insights into the mechanisms of oncogenesis and may aid in the development of targeted cancer therapies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 474010-58-7
Applications Farnesyl Transferase Inhibitor
Formula C26H27N5O5S3
Molecular Weight 585.72
SMILES
CS(=O)(O)=O.O=S(N(CC1=CC(C#N)=CC=C1N(C2)CC3=CN=CN3)[C@@H]2CC4=CC=CC=C4)(C5=CC=CS5)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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