Fig. 1 · Structure
Documents & Downloads
BMS-470539 dihydrochloride
MC-1 Receptor Agonist
BMS-470539 dihydrochloride is a selective agonist of the melanocortin-1 receptor (MC-1R), exhibiting an IC50 of 120 nM and an EC50 of 28 nM. This compound demonstrates potent anti-inflammatory properties while showing no activation of MC-3R and minimal partial agonism at MC-4R and MC-5R. BMS-470539 dihydrochloride is utilized in research focused on inflammatory conditions and the modulation of skin pigmentation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2341796-82-3 |
| Applications | MC-1 Receptor Agonist |
| Formula | C32H43Cl2N5O4 |
| Molecular Weight | 632.62 |
| SMILES | CCCC(C1(C2=CC=CC=C2)CCN(C([C@@H](CC3=CC=C(C=C3)OC)NC([C@H](CC4=CN=CN4C)N)=O)=O)CC1)=O.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.