Fig. 1 · Structure
Documents & Downloads
BMS-538305 hydrochloride
Dipeptidyl Peptidase Inhibitor
BMS-538305 hydrochloride is a potent and selective inhibitor of dipeptidyl peptidase IV (DPP-IV), exerting its biological activity through the formation of a reversible covalent complex with the enzyme. The mechanism of action involves the covalent binding between the nitrile carbon of BMS-538305 and the enzyme residue S630, as revealed by X-ray crystal structure analysis. This compound is primarily utilized in research related to glucose metabolism and diabetes management, making it valuable for studies focused on metabolic disorders and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 841302-51-0 |
| Applications | Dipeptidyl Peptidase Inhibitor |
| Formula | C17H27ClN2O2 |
| Molecular Weight | 326.86 |
| SMILES | O=C(N1[C@@H]2[C@H](CC1)C2)[C@H]([C@@]34C[C@@](C[C@H](C[C@H]5C4)C3)(C5)O)N.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.