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Biological Activity
BMS-707035 is an HIV-1 integrase (IN) inhibitor. HIV-1 integrase (IN) represents a therapeutically advantageous viral target to treat HIV/AIDS in the clinic.
Targets
| HIV-I integrase | ||||
| 15 nM |
| In vitro | DMSO | 32 mg/mL (77.96 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.37 mL | 121.83 mL | 243.66 mL |
| 0.5 mM | 4.87 mL | 24.37 mL | 48.73 mL |
| 1 mM | 2.44 mL | 12.18 mL | 24.37 mL |
| 5 mM | 0.49 mL | 2.44 mL | 4.87 mL |
*The above data is based on the productmolecular weight 410.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10156 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 729607-74-3 |
| Formula | C17H19FN4O5S |
| M. Wt | 410.4 |
| Purity | >98% |
| Synonyms | BMS707035 |
| SMILES | CN1C(=O)C(=C(N=C1N2CCCCS2(=O)=O)C(=O)NCC3=CC=C(C=C3)F)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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