Fig. 1 · Structure
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BMS-986094
HCV Inhibitor
BMS-986094 is a potent inhibitor of hepatitis C virus (HCV) replication, exhibiting an EC50 of 35 nM at 24 hours in Huh-7 cells. This compound acts as a phosphoramidate proagent of 6-O-methyl-2’-C-methyl guanosine, providing significant antiviral activity. BMS-986094 is primarily used in research focused on chronic HCV infection and contributes to the understanding of therapeutic strategies against HCV.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1234490-83-5 |
| Applications | HCV Inhibitor |
| Formula | C30H39N6O9P |
| Molecular Weight | 658.64 |
| Synonyms | INX-08189 |
| SMILES | C[C@]([C@](O[C@@H]1CO[P](OC2=CC=CC3=C2C=CC=C3)(N[C@@H](C)C(OCC(C)(C)C)=O)=O)([H])N4C5=NC(N)=NC(OC)=C5N=C4)([C@@H]1O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.