Fig. 1 · Structure
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BMY 45778
Prostacyclin Receptor Agonist
BMY 45778 is a non-prostanoid prostacyclin receptor agonist. It effectively inhibits platelet aggregation in human (IC50 = 35 nM), rabbit (IC50 = 136 nM), and rat (IC50 = 1.3 μM) models. Additionally, BMY 45778 activates adenylyl cyclase and acts as a partial agonist at the prostacyclin receptor. This compound is valuable for research in cardiovascular biology and thrombosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 152575-66-1 |
| Applications | Prostacyclin Receptor Agonist |
| Formula | C26H18N2O5 |
| Molecular Weight | 438.43 |
| SMILES | O=C(O)COC1=CC=CC(C2=C(C3=NC(C4=CC=CC=C4)=C(C5=CC=CC=C5)O3)N=CO2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.