Fig. 1 · Structure
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BN-82685
CDC25 Inhibitor
BN-82685 is a quinone-based inhibitor of the CDC25 phosphatases, exhibiting potent inhibitory activity with IC50 values of 201 nM for CDC25C, 117 nM for CDC25C-cat, 109 nM for CDC25A, 160 nM for CDC25B2, and 249 nM for CDC25B3. This compound is particularly valuable in cancer research, facilitating studies on cell cycle regulation and phosphatase activity. Its selective targeting of CDC25 enzymes makes it a useful tool for investigating therapeutic strategies in oncology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 477603-18-2 |
| Applications | CDC25 Inhibitor |
| Formula | C12H15N3O2S |
| Molecular Weight | 265.33 |
| Synonyms | IRC-083065 |
| SMILES | O=C(C(NCCN(C)C)=CC1=O)C2=C1SC(C)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.