Fig. 1 · Structure
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BN82002 hydrochloride
CDC25 Phosphatase Inhibitor
BN82002 hydrochloride is a potent and selective irreversible inhibitor of the CDC25 phosphatase family, specifically targeting CDC25A, CDC25B2, CDC25B3, and CDC25C. This compound exhibits IC50 values of 2.4, 3.9, 6.3, and 5.4 µM for its respective targets. BN82002 hydrochloride displays approximately 20-fold greater selectivity for CDC25 over CD45 tyrosine phosphatase, making it a valuable tool for investigating cell cycle regulation and potential therapeutic strategies in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1049740-43-3 |
| Applications | CDC25 Phosphatase Inhibitor |
| Formula | C19H26ClN3O4 |
| Molecular Weight | 395.88 |
| SMILES | O=[N+]([O-])C1=CC=C(CCN(CC2=CC(N(C)C)=CC(OC)=C2O)C)C=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.