Fig. 1 · Structure
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Boc-amido-PEG9-amine
PROTAC Linkers
Boc-amido-PEG9-amine is a polyethylene glycol (PEG)-based linker tailored for PROTAC (Proteolysis Targeting Chimeras) applications. This reagent facilitates the synthesis of PROTAC molecules, enabling targeted protein degradation through an innovative dual-binding mechanism. Its hydrophilic nature enhances solubility and bioavailability, making it an essential component in the development of targeted therapeutics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 890091-43-7 |
| Applications | PROTAC Linkers |
| Formula | C25H52N2O11 |
| Molecular Weight | 556.69 |
| SMILES | O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.