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Boc-azetidine-2C-oxotetrahydropyrimidin-bromophenyl

PROTAC Linker

Boc-azetidine-2C-oxotetrahydropyrimidin-bromophenyl serves as an effective PROTAC linker, facilitating the formation of targeted protein degraders. This compound plays a crucial role in the synthesis of the PROTAC GSPT1 degrader-1, enabling the selective degradation of specific proteins of interest. Its application in chemical research enhances the development of therapies aimed at modulating protein levels in various biological contexts.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3034310-18-1
Applications	PROTAC Linker
Formula	C₂₀H₂₈BrN₃O₃
Molecular Weight	438.36
SMILES	O=C(N(CCC1)C2=CC(Br)=CC=C2)N1CCC3CN(C(OC(C)(C)C)=O)C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.