Fig. 1 · Structure
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Boc-C16-NHS ester
PROTAC Linkers
Boc-C16-NHS ester is an alkyl/ether-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This molecule facilitates the selective degradation of target proteins by promoting the interaction between E3 ubiquitin ligases and the protein of interest. Its ability to enhance the efficacy of PROTACs makes it a valuable reagent in chemical biology and drug discovery research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 843666-34-2 |
| Applications | PROTAC Linkers |
| Formula | C26H45NO6 |
| Molecular Weight | 467.64 |
| SMILES | O=C(OC(C)(C)C)CCCCCCCCCCCCCCCCC(ON1C(CCC1=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.