Boc-C16-NHS ester

Catalog No.: A82399
PROTAC Linkers
Boc-C16-NHS ester is an alkyl/ether-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This molecule facilitates the selective degradation of target proteins by promoting the interaction between E3 ubiquitin ligases and the protein of interest. Its ability to enhance the efficacy of PROTACs makes it a valuable reagent in chemical biology and drug discovery research.
Grouped product items
Size Price Stock Qty
100mg
$30.00
In stock
250mg
$40.00
In stock
1g
$90.00
In stock
5g
$445.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBoc-C16-NHS ester is an alkyl/ether-based linker designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). This molecule facilitates the selective degradation of target proteins by promoting the interaction between E3 ubiquitin ligases and the protein of interest. Its ability to enhance the efficacy of PROTACs makes it a valuable reagent in chemical biology and drug discovery research.
Product Information
Catalog NumA82399
FormulaC26H45NO6
Molecular Weight467.64
CAS Number843666-34-2
SMILESO=C(OC(C)(C)C)CCCCCCCCCCCCCCCCC(ON1C(CCC1=O)=O)=O
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