Fig. 1 · Structure
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Boc-NH-bicyclo1.1.1pentane-C-NH2
PROTAC Linker
Boc-NH-bicyclo[1.1.1]pentane-C-NH2 functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for linking a target protein to an E3 ligase, thereby promoting ubiquitination and subsequent degradation of the target protein. It is valuable in various research applications, including targeted protein degradation studies and exploring protein homeostasis mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1638765-05-5 |
| Applications | PROTAC Linker |
| Formula | C11H20N2O2 |
| Molecular Weight | 212.29 |
| SMILES | O=C(OC(C)(C)C)NC12CC(CN)(C1)C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.