Fig. 1 · Structure
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Boc-NH-C4-acid
PROTAC Linker
Boc-NH-C4-acid is a PROTAC linker that serves as an alkyl/ether chemical moiety. It plays a crucial role in the synthesis of PROTAC1 and facilitates the targeted degradation of key components in the PRC2 complex, including EED, EZH2, and SUZ12. This linker is essential for research involving proteolysis-targeting chimeras, enabling advancements in targeted protein degradation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 27219-07-4 |
| Applications | PROTAC Linker |
| Formula | C10H19NO4 |
| Molecular Weight | 217.26 |
| SMILES | O=C(O)CCCCNC(OC(C)(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.