Fig. 1 · Structure
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Boc-NH-PEG1-OH
PROTAC Linker
Boc-NH-PEG1-OH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the development of PROTACs by providing the requisite solubility and stability, enhancing cellular uptake and target specificity. Its application is essential for advancing research in targeted protein degradation, a promising approach in drug discovery and development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 26690-80-2 |
| Applications | PROTAC Linker |
| Formula | C7H15NO3 |
| Molecular Weight | 161.20 |
| SMILES | O=C(OC(C)(C)C)NCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.