Fig. 1 · Structure
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Boc-NH-PEG2-C2-NHS ester
PROTAC Linkers
Boc-NH-PEG2-C2-NHS ester is an alkyl/ether-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the conjugation of target proteins with E3 ligases, thereby promoting targeted degradation pathways. Its application in chemical biology allows for the development of innovative therapeutic strategies through the modulation of protein levels within cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2183440-73-3 |
| Applications | PROTAC Linkers |
| Formula | C16H26N2O8 |
| Molecular Weight | 374.39 |
| SMILES | CC(C)(C)OC(NCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.