Fig. 1 · Structure
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Boc-NH-PEG4-C2-Boc
PROTAC Linkers
Boc-NH-PEG4-C2-Boc is a PEG-based linker designed for use in PROTAC (Proteolysis Targeting Chimeras) synthesis. This compound facilitates the assembly of bifunctional molecules by connecting a ligand for a target protein with an E3 ligase recruiting moiety, enhancing cellular degradation of targeted proteins. Its properties support diverse biological research applications, particularly in targeted protein degradation studies and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2138484-13-4 |
| Applications | PROTAC Linkers |
| Formula | C20H39NO8 |
| Molecular Weight | 421.53 |
| SMILES | O=C(OC(C)(C)C)CCOCCOCCOCCOCCNC(OC(C)(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.