Fig. 1 · Structure
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Boc-NH-PEG5-CH2CH2COOH
PROTAC Linker
Boc-NH-PEG5-CH2CH2COOH is a PEG-based linker designed for use in the synthesis of PROTAC (Proteolysis Targeting Chimeras). This compound facilitates the development of bifunctional molecules that can selectively target and degrade specific proteins, thereby enabling advanced studies in targeted protein degradation and therapeutic applications. Its incorporation in PROTAC design may enhance solubility and bioavailability of the resultant complexes, making it a valuable tool in chemical biology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1347750-78-0 |
| Applications | PROTAC Linker |
| Formula | C18H35NO9 |
| Molecular Weight | 409.47 |
| SMILES | O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.