Boc-NHCH2-Ph-pyrimidine-NH2

Catalog No.: A83874
PROTAC Linker
Boc-NHCH2-Ph-pyrimidine-NH2 serves as a versatile linker for PROTAC (Proteolysis Targeting Chimeras) applications. By facilitating the conjugation of target proteins with E3 ligases, this compound enhances the selective degradation of proteins of interest. Its unique structure allows for improved target engagement and therapeutic potency, making it an essential tool for drug discovery and chemical biology research focused on targeted protein degradation.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBoc-NHCH2-Ph-pyrimidine-NH2 serves as a versatile linker for PROTAC (Proteolysis Targeting Chimeras) applications. By facilitating the conjugation of target proteins with E3 ligases, this compound enhances the selective degradation of proteins of interest. Its unique structure allows for improved target engagement and therapeutic potency, making it an essential tool for drug discovery and chemical biology research focused on targeted protein degradation.
Product Information
Catalog NumA83874
FormulaC16H20N4O2
Molecular Weight300.36
CAS Number3040121-15-8
SMILESO=C(OC(C)(C)C)NCC(C=C1)=CC=C1C2=NC=C(N)C=N2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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