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Boc-NHCH2-Ph-pyrimidine-NH2

PROTAC Linker

Boc-NHCH2-Ph-pyrimidine-NH2 serves as a versatile linker for PROTAC (Proteolysis Targeting Chimeras) applications. By facilitating the conjugation of target proteins with E3 ligases, this compound enhances the selective degradation of proteins of interest. Its unique structure allows for improved target engagement and therapeutic potency, making it an essential tool for drug discovery and chemical biology research focused on targeted protein degradation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3040121-15-8
Applications	PROTAC Linker
Formula	C₁₆H₂₀N₄O₂
Molecular Weight	300.36
SMILES	O=C(OC(C)(C)C)NCC(C=C1)=CC=C1C2=NC=C(N)C=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.