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Boc-VC-PAB-MMAF

Catalog No.: A43044
ADC Linker
Boc-VC-PAB-MMAF is a cleavable linker designed for the construction of antibody-drug conjugates (ADCs). This compound facilitates targeted delivery of cytotoxic agents to tumor cells, providing insights into the efficacy and mechanisms of cancer treatment. It is particularly useful in cancer research, enabling the development of innovative therapeutic strategies that enhance selective tumor targeting while minimizing systemic toxicity.
Boc-VC-PAB-MMAF 2091306-13-5 ADC Linker
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBoc-VC-PAB-MMAF is a cleavable linker designed for the construction of antibody-drug conjugates (ADCs). This compound facilitates targeted delivery of cytotoxic agents to tumor cells, providing insights into the efficacy and mechanisms of cancer treatment. It is particularly useful in cancer research, enabling the development of innovative therapeutic strategies that enhance selective tumor targeting while minimizing systemic toxicity.
Product Information
Catalog NumA43044
FormulaC63H100N10O15
Molecular Weight1237.53
CAS Number2091306-13-5
SMILESOC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OC(C)(C)C)=O)=O)=O)=O)=O)=O)=O)OC)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

Antibody-drug Conjugates (ADC) > ADC Linker