BocNH-PEG2-CH2COONHS is a PEG-derived biochemical assay reagent that features a terminal carboxylic acid and a Boc-protected amino group. This hydrophilic PEG spacer enhances the solubility of compounds in aqueous solutions, facilitating diverse biochemical applications. The terminal carboxylic acid readily reacts with primary amine groups, particularly in conjunction with activators like EDC and HATU, to yield stable amide bonds. Deprotection of the Boc group under mild acidic conditions generates a free amine for subsequent reactions.
BocNH-PEG2-CH2COONHS is a PEG-derived biochemical assay reagent that features a terminal carboxylic acid and a Boc-protected amino group. This hydrophilic PEG spacer enhances the solubility of compounds in aqueous solutions, facilitating diverse biochemical applications. The terminal carboxylic acid readily reacts with primary amine groups, particularly in conjunction with activators like EDC and HATU, to yield stable amide bonds. Deprotection of the Boc group under mild acidic conditions generates a free amine for subsequent reactions.
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