BocNH-PEG5-CH2CH2Br is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound effectively facilitates the conjugation of target proteins to E3 ligases, promoting the ubiquitin-proteasome pathway for targeted protein degradation. Its structural features enhance solubility and optimal spatial orientation, making it suitable for research applications in drug development and protein modulation studies.
BocNH-PEG5-CH2CH2Br is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound effectively facilitates the conjugation of target proteins to E3 ligases, promoting the ubiquitin-proteasome pathway for targeted protein degradation. Its structural features enhance solubility and optimal spatial orientation, making it suitable for research applications in drug development and protein modulation studies.
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