Fig. 1 · Structure
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Bodipy C12-ceramide
Fluorescently Tagged Form of C12-Ceramide
Bodipy C12-ceramide (B12Cer) is a fluorescently labeled derivative of C12-Ceramide, characterized by excitation and emission maxima at 505 nm and 540 nm, respectively. This compound is formed through the hydrolysis of BODIPY-C12 sphingomyelin by acid sphingomyelinase in vitro. Bodipy C12-ceramide is primarily utilized for quantifying acid sphingomyelinase activity in plasma samples, particularly in studies related to Niemann-Pick disease, facilitating insights into sphingolipid metabolism and associated pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1246355-58-7 |
| Applications | Fluorescently Tagged Form of C12-Ceramide |
| Formula | C42H70BF2N3O3 |
| Molecular Weight | 713.83 |
| SMILES | CC1=CC(C)=[N+]2C1=C(CCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)CO)=O)C3=C(C)C=C(C)N3[B-]2(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.