Bodipy C12-ceramide (B12Cer) is a fluorescently labeled derivative of C12-Ceramide, characterized by excitation and emission maxima at 505 nm and 540 nm, respectively. This compound is formed through the hydrolysis of BODIPY-C12 sphingomyelin by acid sphingomyelinase in vitro. Bodipy C12-ceramide is primarily utilized for quantifying acid sphingomyelinase activity in plasma samples, particularly in studies related to Niemann-Pick disease, facilitating insights into sphingolipid metabolism and associated pathologies.
Bodipy C12-ceramide (B12Cer) is a fluorescently labeled derivative of C12-Ceramide, characterized by excitation and emission maxima at 505 nm and 540 nm, respectively. This compound is formed through the hydrolysis of BODIPY-C12 sphingomyelin by acid sphingomyelinase in vitro. Bodipy C12-ceramide is primarily utilized for quantifying acid sphingomyelinase activity in plasma samples, particularly in studies related to Niemann-Pick disease, facilitating insights into sphingolipid metabolism and associated pathologies.
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