Fig. 1 · Structure
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BODIPY-FL staurosporine
Fluorescence Probe
BODIPY-FL staurosporine is a fluorescence probe that targets tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases with high specificity. This compound facilitates the development of binding assays for various kinases, including PIM3, CDC42BPG, MAP2K7, TXK, and SIK3, which are not well-suited for Kinase Tracer 236. BODIPY-FL staurosporine serves as a valuable tool in the analysis of kinase selectivity, enhancing the drug discovery process for kinase inhibitors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2411845-57-1 |
| Applications | Fluorescence Probe |
| Formula | C49H54BF2N7O7 |
| Molecular Weight | 901.80 |
| SMILES | C[C@]12N3C4=C(C5=CC=CC=C53)C(CNC6=O)=C6C7=C4N([C@](C[C@H]([C@H]2OC)NCCOCCOCCOCCNC(CCC8=CC=C(C=C9C(C)=C%10)[N-]8[B+3]([F-])([F-])[N]9=C%10C)=O)([H])O1)C%11=CC=CC=C7%11 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.