Bosentan Hydrate

Catalog No.: A14944
ET-A and ET-B antagonist
Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
Grouped product items
Product Name Price Stock Qty
Bosentan Hydrate 50mg
$60.00
In stock
Bosentan Hydrate 100mg
$100.00
In stock
Bosentan Hydrate 500mg
$300.00
In stock
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Biological Activity
Discription Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
Product Information
Catalog Num A14944
Formula C27H29N5O6S.H2O
Molecular Weight 569.63
CAS Number 157212-55-0
SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC.O
Synonyms Ro 47-0203
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO 92 mg/mL (161.51 mM)
Water Insoluble
Ethanol 2 mg/mL (3.51 mM)
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.56 mL 87.78 mL 175.55 mL
0.5 mM 3.51 mL 17.56 mL 35.11 mL
1 mM 1.76 mL 8.78 mL 17.56 mL
5 mM 0.35 mL 1.76 mL 3.51 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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