Bosentan Hydrate
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. |
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Catalog Num | A14944 |
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Formula | C27H29N5O6S.H2O |
Molecular Weight | 569.63 |
CAS Number | 157212-55-0 |
SMILES | CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC.O |
Synonyms | Ro 47-0203 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 92 mg/mL (161.51 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (3.51 mM) | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.56 mL | 87.78 mL | 175.55 mL |
0.5 mM | 3.51 mL | 17.56 mL | 35.11 mL |
1 mM | 1.76 mL | 8.78 mL | 17.56 mL |
5 mM | 0.35 mL | 1.76 mL | 3.51 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2