Fig. 1 · Structure
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BPH-1218
Anti-infective Agent
BPH-1218 is a potent inhibitor of squalene synthase (SQS), demonstrating IC50 values of 31 nM for Trypanosoma cruzi SQS and 64 nM for human SQS. This compound exhibits significant anti-infective activity, making it a valuable tool for research aimed at developing therapeutic strategies against parasitic infections. Its specificity towards SQS underscores its potential in studying lipid metabolism and related pathways in both parasitic and human cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1426824-36-3 |
| Applications | Anti-infective Agent |
| Formula | C15H30N2O6P2 |
| Molecular Weight | 396.36 |
| SMILES | O=P(O)(C(P(O)(O)=O)C[N+]1=CN(CCCCCCCCCC)C=C1)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.