Fig. 1 · Structure

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Br-Boc-C2-azido

PROTAC Linker

Br-Boc-C2-azido is a specialized PROTAC linker featuring an azide group that facilitates the synthesis of PROTACs through click chemistry. This compound can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes and can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified molecules. Its versatile reactivity makes it a valuable tool for researchers in the development of targeted protein degradation technologies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1120364-53-5
Applications PROTAC Linker
Formula C6H10BrN3O2
Molecular Weight 236.07
SMILES
CC(C)(Br)C(OCCN=[N+]=[N-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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