Br-Boc-C2-azido is a specialized PROTAC linker featuring an azide group that facilitates the synthesis of PROTACs through click chemistry. This compound can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes and can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified molecules. Its versatile reactivity makes it a valuable tool for researchers in the development of targeted protein degradation technologies.
Br-Boc-C2-azido is a specialized PROTAC linker featuring an azide group that facilitates the synthesis of PROTACs through click chemistry. This compound can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkynes and can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-modified molecules. Its versatile reactivity makes it a valuable tool for researchers in the development of targeted protein degradation technologies.
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