Fig. 1 · Structure
Documents & Downloads
Br-PEG4-OH
PROTAC Linkers
Br-PEG4-OH is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTACs (proteolysis targeting chimeras). This compound facilitates the connection between a target protein and an E3 ligase, promoting targeted protein degradation. It serves as a crucial building block in the development of therapeutic agents aimed at modulating protein levels in various biological pathways, making it valuable for research in cancer and other diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 85141-94-2 |
| Applications | PROTAC Linkers |
| Formula | C8H17BrO4 |
| Molecular Weight | 257.12 |
| SMILES | BrCCOCCOCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.