Signaling Pathway
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| Discription | Branebrutinib (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Bruton??s tyrosine kinase (BTK), with an IC50 of 0.1 nM. |
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| Catalog Num | A20043 |
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| Formula | C20H23FN4O2 |
| Molecular Weight | 370.42 |
| CAS Number | 1912445-55-6 |
| SMILES | O=C(C1=CC(F)=C(N2C[C@@H](NC(C#CC)=O)CCC2)C3=C1NC(C)=C3C)N |
| Synonyms | BMS-986195, BMS986195, BMS 986195 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 73 mg/mL (197.07 mM) | |
| Water | Insoluble | ||
| Ethanol | 38 mg/mL (102.58 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27 mL | 134.98 mL | 269.96 mL |
| 0.5 mM | 5.4 mL | 27 mL | 53.99 mL |
| 1 mM | 2.7 mL | 13.5 mL | 27 mL |
| 5 mM | 0.54 mL | 2.7 mL | 5.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
