Fig. 1 · Structure
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Brasofensine maleate
Monoamine Reuptake Blocker
Brasofensine maleate is a selective monoamine reuptake blocker, primarily acting as a dopamine transporter antagonist. This compound demonstrates the ability to enhance dopaminergic signaling, making it relevant for research in Parkinson's disease and other neurodegenerative disorders. Its oral bioavailability supports in vivo studies aimed at exploring therapeutic strategies for dopamine-related pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 173830-14-3 |
| Applications | Monoamine Reuptake Blocker |
| Formula | C20H24Cl2N2O5 |
| Molecular Weight | 443.32 |
| Synonyms | BMS-204756 maleate |
| SMILES | CN1[C@@]2([H])[C@H](/C=N/OC)[C@@H](C3=CC=C(Cl)C(Cl)=C3)C[C@]1([H])CC2.O=C(/C=C\C(O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.