Fig. 1 · Structure
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BRD0476
Apoptosis Inhibitor
BRD0476 is a potent apoptosis inhibitor targeting pancreatic β-cells, demonstrating an EC50 value of 0.78 μM and achieving maximal inhibitory activity of 99%. This compound is suitable for applications in diabetes research, particularly in studies aimed at understanding β-cell survival and the mechanisms underlying diabetic pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1314958-91-2 |
| Applications | Apoptosis Inhibitor |
| Formula | C35H38N4O8S |
| Molecular Weight | 674.76 |
| Synonyms | ML187 |
| SMILES | O=C(NC1=C(C2=CC=C1)O[C@H]([C@@H](CN(C2=O)[C@H](CO)C)C)CN(C)S(=O)(C3=CC=C4OCCOC4=C3)=O)NC5=C6C=CC=CC6=CC=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.